Japanese research institutions are deeply exploring the molecular mechanisms of aging and actively developing nutrients that can influence the aging process.

Newly Established Research Institution: In August 2025, the Gakken Group and Kyoto University jointly established a new company called 'Gerok,' focusing on anti-aging research and the translation of its results. The company emphasizes functional analysis and drug development centered on the anti-aging gene α-Klotho.

A New Discovery of Vitamin B3 Derivatives: Collaborative clinical research between Chiba University in Japan and the U.S. National Institute on Aging has demonstrated that a vitamin B3 derivative, nicotinamide riboside (NR), can effectively increase cellular coenzyme NAD levels. Intake of NR not only improves vascular elasticity and delays arteriosclerosis, but it can also alleviate chronic skin ulcers and support kidney function. NR is expected to be applied as a novel nutritional intervention to slow down age-related functional declines.